P62/SQSTM1 mediates the autophagy-lysosome degradation of CDK2 protein undergoing PI3Kα/AKT T308 inhibition

Author:

Zhang ChaoORCID,Zhang Hong-Liang,Liu Shan-Ling,Yang Jun-Mei,Gao Feng-Hou

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference36 articles.

1. Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities;Zabihi;J. Cancer Res. Clin. Oncol.,2022

2. Cell cycle control in cancer;Matthews;Nat. Rev. Mol. Cell Biol.,2022

3. A unique CDK4/6 inhibitor: current and future therapeutic strategies of abemaciclib;Chong;Pharmacol. Res.,2020

4. CDK inhibitors in cancer therapy, an overview of recent development;Zhang;Am J. Cancer Res.,2021

5. Cyclin E/CDK2: DNA replication, replication stress and genomic instability;Fagundes;Front. Cell Dev. Biol.,2021

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