Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2-Reference-Cited by-同舟云学术

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Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2

Published:2013-05 Issue:3 Volume:434 Page:600-605
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Koo Jung Eun,Park Zee-Yong,Kim Nam Doo,Lee Joo Young

Funder

National Research Foundation of Korea (NRF) funded by the Korean government (MEST)

National R&D Program for Cancer Control, Ministry of Health & Welfare, Republic of Korea

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference18 articles.

1. Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa;Ohto;Science,2007

2. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4;Shimazu;Jounal of Experimental Medicie,1999

3. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex;Park;Nature,2009

4. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors;Kawai;Nature Immunology,2010

5. Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids;Lee;Nutrition Reviews,2010

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