PAX3 mutation suppress otic progenitors proliferation and induce apoptosis by inhibiting WNT1/β-catenin signaling pathway in WS1 patient iPSC-derived inner ear organoids

Author:

Li SiJun,He Chufeng,Mei Lingyun,Wu Xuewen,Feng Yong,Song JianORCID

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference30 articles.

1. Waardenburg syndrome;Read;J. Med. Genet.,1997

2. Waardenburg syndrome (WS): the analysis of a single family with a WS1 mutation showing linkage to RFLP markers on human chromosome 2q;Asher;Am. J. Hum. Genet.,1991

3. Dual embryonic origin of the mammalian otic vesicle forming the inner ear;Freyer;Development,2011

4. Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest;Manderfield;Cell Rep.,2014

5. PAX3 and PAX7 as upstream regulators of myogenesis;Buckingham;Semin. Cell Dev. Biol.,2015

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