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TREM2 modulates microglia phenotypes in the neuroinflammation of Parkinson's disease

  • Published:2018-05 Issue:4 Volume:499 Page:797-802
  • ISSN:0006-291X
  • Container-title:Biochemical and Biophysical Research Communications
  • language:en
  • Short-container-title:Biochemical and Biophysical Research Communications

Author:

Zhang Youwen,Feng Shujun,Nie Kun,Li Yan,Gao Yuyuan,Gan Rong,Wang Limin,Li Bing,Sun Xuegang,Wang LijuanORCID,Zhang YuhuORCID

Funder

Key Program of Natural Science Foundation of Guangdong Province, China

Natural Science Foundation of Guangdong Province, China

Medical Research Fund of Guangdong Province, China

National Key Research and Development Plan of China

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference32 articles.

1. TREM2 and neurodegenerative disease;Benitez;N. Engl. J. Med.,2013

2. Human glia can both induce and rescue aspects of disease phenotype in Huntington disease;Benraiss;Nat. Commun.,2016

3. Staging of brain pathology related to sporadic Parkinson's disease;Braak;Neurobiol. Aging,2003

4. TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis;Cady;JAMA Neurol,2014

5. Assessing activation states in microglia;Colton;CNS Neurol. Disord. - Drug Targets,2010
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