The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux
Author:
Funder
NIH NHGRI Center of Excellence in Genomic Science
NIH Common Fund LINCS
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference41 articles.
1. Activation and regulation of the inflammasomes;Latz;Nat. Rev. Immunol.,2013
2. Caspase-1-induced pyroptotic cell death;Miao;Immunol. Rev.,2011
3. Pro-inflammatory programmed cell death;Cookson;Trends Microbiol.,2001
4. Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function;Ghonime;J. Immunol.,2014
5. Toll-like receptor signalling;Akira;Nat. Rev. Immunol.,2004
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Interrogating direct NLRP3 engagement and functional inflammasome inhibition using cellular assays;Cell Chemical Biology;2023-10
2. Syk inhibitor R406 downregulates inflammation in an in vitro model of Pseudomonas aeruginosa infection;Canadian Journal of Physiology and Pharmacology;2018-02
3. Nanoparticle‐Based Fluoroionophore for Analysis of Potassium Ion Dynamics in 3D Tissue Models and In Vivo;Advanced Functional Materials;2018-01-05
4. Length, but Not Reactive Edges, of Cup-stack MWCNT Is Responsible for Toxicity and Acute Lung Inflammation;Toxicologic Pathology;2017-09-25
5. NLRP3 inflammasome activation results in liver inflammation and fibrosis in mice infected with Schistosoma japonicum in a Syk-dependent manner;Scientific Reports;2017-08-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3