Central nervous system specific high molecular weight ALS2/alsin homophilic complex is enriched in mouse brain synaptosomes
Author:
Funder
Japan Society for the Promotion of Science
Tokai University School of Medicine
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference24 articles.
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2. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2;Hadano;Nat. Genet.,2001
3. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis;Yang;Nat. Genet.,2001
4. ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics;Otomo;Hum. Mol. Genet.,2003
5. Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking;Hadano;PLoS One,2010
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