Unraveling the mechanism of carbonic anhydrase IX inhibition by alkaloids from Ruta chalepensis: A synergistic analysis of in vitro and in silico data

Author:

Alqhtani Haifa A.,Othman Sarah I.,Aba Alkhayl Faris F.,Altoom Naif G.,Lamsabhi Al MokhtarORCID,Kamel Emadeldin M.ORCID

Funder

Ministerio de Ciencia, Innovación y Universidades

Community of Madrid

Princess Nourah bint Abdulrahman University

Publisher

Elsevier BV

Reference58 articles.

1. Carbonic anhydrase IX: an atypical target for innovative therapies in cancer;Ronca;Biochim. Biophys. Acta Rev. Canc,2024

2. How and why are cancers acidic? Carbonic anhydrase IX and the homeostatic control of tumour extracellular pH;Lee;Cancers,2020

3. Carbonic anhydrase IX and acid transport in cancer;Becker;Br. J. Cancer,2020

4. Carbonic anhydrase IX: a tumor acidification switch in heterogeneity and chemokine regulation;Queen;Semin. Cancer Biol.,2022

5. Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents;Supuran,2021

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