Acetaminophen analog N -acetyl- m -aminophenol, but not its reactive metabolite, N -acetyl- p -benzoquinone imine induces CYP3A activity via inhibition of protein degradation-Reference-Cited by-同舟云学术

Acetaminophen analog N -acetyl- m -aminophenol, but not its reactive metabolite, N -acetyl- p -benzoquinone imine induces CYP3A activity via inhibition of protein degradation

Published:2017-05 Issue:3 Volume:486 Page:639-644
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Santoh Masataka,Sanoh Seigo^ORCID,Ohtsuki Yuya,Ejiri Yoko,Kotake Yaichiro,Ohta Shigeru

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference23 articles.

1. Prevalence of non-cytochrome P450-Mediated metabolism in food and drug administration-approved oral and intravenous drugs: 2006-2015;Cerny;Drug Metab. Dispos.,2016

2. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol. Ther.,2013

3. Expression of hepatic drug-metabolizing cytochrome p450 enzymes and their intercorrelations: a meta-analysis;Achour;Drug Metab. Dispos.,2014

4. Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities;Ohtsuki;Drug Metab. Dispos.,2012

5. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR;Tolson;Adv. Drug Deliv. Rev.,2010

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acetaminophen induces mitochondrial apoptosis through proteasome dysfunctions;Life Sciences;2024-07

2. Transcriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region;Scientific Reports;2024-05-15

3. Variation in Expression of Cytochrome P450 3A Isoforms and Toxicological Effects: Endo- and Exogenous Substances as Regulatory Factors and Substrates;Biological and Pharmaceutical Bulletin;2021-11-01

4. Preliminary Study on Hepatoprotective Effect and Mechanism of (-)-Epigallocatechin-3-gallate against Acetaminophen-induced Liver Injury in Rats;IRAN J PHARM RES;2021

5. Phosphorylation of Acetylaminophenols with Secondary Phosphine Chalcogenides: Synthesis of O-(Acetylamino)phenyl Chalcogenophosphinates;Russian Journal of General Chemistry;2019-01