High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1

Author:

Hashizume Misato,Mihara Masahiko

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference34 articles.

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2. Effects of interleukin-6 on proliferation and proteoglycan metabolism in articular chondrocyte cultures;Jikko;Cell Biol. Med.,1998

3. Effects of hyaluronan on proteoglycan content of osteoarthritic chondrocytes in vitro;Stove;J. Orthop. Res.,2002

4. Hyaluronans in the treatment of osteoarthritis of the knee; evidence for disease-modifying activity;Goldberg;Osteoarthritis Cartilage,2005

5. Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanism of action;Moreland;Arthritis Res. Ther.,2003

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