Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding-Reference-Cited by-同舟云学术

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Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding

Published:2010-03 Issue:4 Volume:393 Page:688-693
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Istrate Monica A.,Nussler Andreas K.,Eichelbaum Michel,Burk Oliver

Funder

Deutsche Forschungsgemeinschaft

Bosch Foundation

German Federal Ministry of Education and Research

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference31 articles.

1. In vitro and in vivo drug interactions involving human CYP3A;Thummel;Annu. Rev. Pharmacol. Toxicol.,1998

2. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions;Lehmann;J. Clin. Invest.,1998

3. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module;Goodwin;Mol. Pharmacol.,1999

4. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha;Liu;Biochem. J.,2008

5. Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics;Toriyabe;Mol. Pharmacol.,2009

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