Constitutive androstane receptor activation evokes the expression of glycolytic genes
Author:
Funder
Russian Foundation for Basic Research
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference38 articles.
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2. Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha;Miao;J. Biol. Chem.,2006
3. Constitutive androstane receptor activation by 2,4,6-triphenyldioxane-1,3 suppresses the expression of the gluconeogenic genes;Kachaylo;Eur. J. Pharmacol.,2012
4. The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity;Yarushkin;Br. J. Pharmacol.,2013
5. Activation of the constitutive androstane receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way;Marmugi;Toxicol. Appl. Pharmacol.,2016
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1. Clinical Relevance of the Constitutive Androstane Receptor;Drug Metabolism and Disposition;2022-03-02
2. GCN5-mediated PKM2 acetylation participates in benzene-induced hematotoxicity through regulating glycolysis and inflammation via p-Stat3/IL17A axis;Environmental Pollution;2022-02
3. The xenobiotic receptors PXR and CAR in liver physiology, an update;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2021-06
4. Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR;Cells;2020-10-15
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