The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1)-Reference-Cited by-同舟云学术

The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1)

Published:2013-10 Issue:3 Volume:440 Page:443-448
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Courilleau Delphine,Bouyssou Pascal,Fischmeister Rodolphe,Lezoualc’h Frank,Blondeau Jean-Paul

Funder

Région Midi-Pyrénées, the Centre National de la Recherche Scientifique (PIR Innovation Thérapeutique 2010) and by the Investment for the Future program

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference18 articles.

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2. Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs;de Rooij;J. Biol. Chem.,2000

3. Rap-linked cAMP signaling Epac proteins: compartmentation, functioning and disease implications;Breckler;Cell. Signal.,2011

4. Pharmacological PKA inhibition: all may not be what it seems;Murray;Sci. Signal.,2008

5. A novel Epac-specific cAMP analog demonstrates independent regulation of Rap1 and ERK;Enserink;Nat. Cell Biol.,2002

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