The N-terminal strand modulates immunoglobulin light chain fibrillogenesis

Author:

del Pozo-Yauner Luis,Wall Jonathan S.,González Andrade Martín,Sánchez-López Rosana,Rodríguez-Ambriz Sandra L.,Pérez Carreón Julio I.,Ochoa-Leyva Adrián,Fernández-Velasco D. Alejandro

Funder

Consejo Nacional de Ciencia y Tecnología (CONACYT)

L. del Pozo-Yauner

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference18 articles.

1. Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates;Khurana;Biochemistry,2001

2. Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains;del Pozo Yauner;Proteins,2008

3. Tertiary structure of human lambda 6 light chains amyloid;Pokkuluri;Int. J. Exp. Clin. Invest. Official J. the Int. Soc. Amyloidosis,1999

4. A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis;Hernandez-Santoyo;J. Mol. Biol.,2010

5. Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation;Richardson;Proc. Natl. Acad. Sci. USA,2002

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