ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line-Reference-Cited by-同舟云学术

ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line

Published:2011-06 Issue:4 Volume:409 Page:738-744
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Bogurcu Nuray,Sevimli-Gur Canan,Ozmen Besra,Bedir Erdal,Korkmaz Kemal Sami

Funder

TUBITAK (The Scientific and Technical Research Council of Turkey)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference22 articles.

1. A.A.N. Papageorgiou V.P., Couladouros E. A., The chemistry and biology of alkannin shikonin and related naphthazarin natural products, Angewandte Chemie İnternational Edition (1999) 270–301.

2. Cellular pharmacology studies of shikonin derivatives;Chen;Phytother. Res.,2002

3. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c and sequential activation of caspases in human colorectal carcinoma cells;Hsu;J. Agric. Food Chem.,2004

4. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells;Mao;Cell Res.,2008

5. Synthesis and biological activity of novel shikonin analogues;Wang;Bioorg. Med. Chem. Lett.,2009

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. β,β-Dimethylacrylalkannin, a Natural Naphthoquinone, Inhibits the Growth of Hepatocellular Carcinoma Cells by Modulating Tumor-Associated Macrophages;Molecules;2024-08-20

2. Targeting matrix metalloproteinases by E3 ubiquitin ligases as a way to regulate the tumor microenvironment for cancer therapy;Seminars in Cancer Biology;2022-11

3. 2,5-Diketopiperazines From a Sponge-Derived Fungus Aspergillus sclerotiorum;Frontiers in Microbiology;2022-05-20

4. ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L;Cell Death & Disease;2021-07-31

5. Alkannin-Induced Oxidative DNA Damage Synergizes With PARP Inhibition to Cause Cancer-Specific Cytotoxicity;Frontiers in Pharmacology;2020-12-22