Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference18 articles.
1. Reconstitution of gamma-secretase activity;Edbauer;Nat. Cell Biol.,2003
2. Skeletal and CNS defects in presenilin-1-deficient mice;Shen;Cell,1997
3. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells;Palacino;J. Biol. Chem.,2000
4. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency;Herreman;Proc. Natl. Acad. Sci. USA,1999
5. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases;Johnson;Science,2002
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Progesterone Suppresses Cholesterol Esterification in APP/PS1 mice and a cell model of Alzheimer’s Disease;Brain Research Bulletin;2021-08
2. Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype;Neurobiology of Aging;2016-10
3. Early pancreatic islet fate and maturation is controlled through RBP-Jκ;Scientific Reports;2016-05-31
4. Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model;Oncogene;2014-02-10
5. Notch1 modulates oxidative stress induced cell death through suppression of apoptosis signal-regulating kinase 1;Proceedings of the National Academy of Sciences;2013-04-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3