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Statins inhibit expression of Thioredoxin reductase 1 in rat and human liver and reduce tumour development

  • Published:2012-01 Issue:3 Volume:417 Page:1046-1051
  • ISSN:0006-291X
  • Container-title:Biochemical and Biophysical Research Communications
  • language:en
  • Short-container-title:Biochemical and Biophysical Research Communications

Author:

Skogastierna Cristine,Johansson Maria,Parini Paolo,Eriksson Mats,Eriksson Lennart C.,Ekström Lena,Björkhem-Bergman Linda

Funder

Pfizer

Swedish Heart and Lung Foundation

Karolinska Institutet

Swedish Science Council

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference29 articles.

1. Effectiveness of statin therapy in adults with coronary heart disease;Wilt;Arch. Intern. Med.,2004

2. Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation;Bjorkhem-Bergman;Anticancer Res.,2010

3. Statins reduce the risk of lung cancer in humans: a large case–control study of US veterans;Khurana;Chest,2007

4. Statins and the risk of colorectal cancer;Poynter;N. Engl. J. Med.,2005

5. A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity;Tamura;Proc. Natl. Acad. Sci. USA,1996
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