A new method for analysis of mitochondrial DNA point mutations and assess levels of heteroplasmy

Author:

Cassandrini Denise,Calevo Maria Grazia,Tessa Alessandra,Manfredi Giovanni,Fattori Fabiana,Meschini Maria Chiara,Carrozzo Rosalba,Tonoli Emmanuel,Pedemonte Marina,Minetti Carlo,Zara Federico,Santorelli Filippo M.,Bruno Claudio

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference21 articles.

1. Mitochondrial respiratory-chain diseases;DiMauro;N. Engl. J. Med.,2003

2. Mitochondrial DNA analysis in clinical laboratory diagnostics;Wong;Clin. Chim. Acta,2005

3. The mitochondrial tRNA(Leu(UUR)) mutation in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS): genetic, biochemical, and morphological correlations in skeletal muscle;Moraes;Am. J. Hum. Genet.,1992

4. Diagnosis of mitochondrial disease: assessment of mitochondrial DNA heteroplasmy in blood;Taylor;Biochem. Biophys. Res. Commun.,1998

5. Mutation screening of the mitochondrial genome using denaturing high-performance liquid chromatography;Biggin;Mol. Genet. Metab.,2005

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