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Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation

  • Published:2017-04 Issue:2 Volume:485 Page:446-453
  • ISSN:0006-291X
  • Container-title:Biochemical and Biophysical Research Communications
  • language:en
  • Short-container-title:Biochemical and Biophysical Research Communications

Author:

Li Dezhi,Gong Rui,Zheng Jun,Chen Xihai,Dimitrov Dimiter S.,Zhao QiORCID

Funder

Guangdong Science and Technology Program

Natural Science Foundation of Guangdong

Shenzhen Peacock Innovation Plan Fund

Shenzhen Knowledge Innovation Program

Macau Science and Technology Development Fund

Intramural Research Program of University of Macau

Intramural Research Program of the NIH

National Cancer Institute

Center for Cancer Research

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference31 articles.

1. Therapeutic antibodies, vaccines and antibodyomes;Dimitrov;MAbs,2010

2. Generation of bispecific antibodies by Fc heterodimerization and their application;Chen;Curr. Pharm. Biotechnol.,2016

3. Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors;Jain;Cancer Res.,1990

4. Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers;Chen;Proc. Natl. Acad. Sci. U. S. A.,2008

5. Engineered CH2 domains (nanoantibodies);Dimitrov;MAbs,2009

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