Sortilin-related receptor 1 interacts with amyloid precursor protein and is activated by 6-shogaol, leading to inhibition of the amyloidogenic pathway

Author:

Na Ji-Young,Song Kibbeum,Lee Ju-Woon,Kim Sokho,Kwon Jungkee

Funder

National Research Foundation of Korea

Korean government

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference27 articles.

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3. LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease;Dodson;J. neuropathology Exp. neurology,2006

4. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production;Herskowitz;J. Biol. Chem.,2011

5. beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms;Haass;J. Biol. Chem.,1993

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