Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells

Author:

Shibuya Akiko,Onda Kenji,Kawahara Hirofumi,Uchiyama Yuka,Nakayama Hiroko,Omi Takamasa,Nagaoka Masayoshi,Matsui Hirofumi,Hirano Toshihiko

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference17 articles.

1. Inhibition of 15-hydroxy prostaglandin dehydrogenase and increase of prostaglandin E2: effect of sofalcone on rat gastric mucosa;Muramatsu;Life Sci.,1987

2. Effect of sofalcone on adherence, production of vacuolating toxin, and induction of interleukin-8 secretion by Helicobacter pylori;Kamiya;J. Clin. Gastroenterol.,1997

3. Inhibitory effect of sofalcone on tumor necrosis factor-alpha and interleukin-1 beta production in human monocytes stimulated by Helicobacter pylori water extract;Fujiwara;Drugs Exp. Clin. Res.,2001

4. Pharmacological and clinical aspects of heme oxygenase;Abraham;Pharmacol. Rev.,2008

5. Heme oxygenase-1 protects gastric mucosal cells against non-steroidal anti-inflammatory drugs;Aburaya;J. Biol. Chem.,2006

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