Dexrazoxane ameliorates doxorubicin-induced cardiotoxicity by inhibiting both apoptosis and necroptosis in cardiomyocytes

Author:

Yu Xiaoxue,Ruan Yang,Huang Xiuqing,Dou Lin,Lan Ming,Cui Ju,Chen BeidongORCID,Gong Huan,Wang Que,Yan Mingjing,Sun Shenghui,Qiu Quan,Zhang Xiyue,Man Yong,Tang Weiqing,Li Jian,Shen TaoORCID

Funder

National Natural Science Foundation of China

Beijing Natural Science Foundation

Beijing Hospital Nova project

Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences

Special Subsidy Project of Beijing Municipal Science and Technology Commission on the Application Research of Capital Clinical Characteristics

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference39 articles.

1. Proteinaceous secretory metabolites of probiotic human commensal Enterococcus hirae 20c, E. Faecium 12a and L12b as antiproliferative agents against cancer cell lines;Sharma;Front. Microbiol.,2018

2. MiR-21 protected cardiomyocytes against doxorubicin-induced apoptosis by targeting BTG2;Tong;Int. J. Mol. Sci.,2015

3. Higenamine combined with [6]-Gingerol suppresses doxorubicin-triggered oxidative stress and apoptosis in cardiomyocytes via upregulation of PI3K/akt pathway;Chen;Evid. Based Complement Altern. Med. : eCAM,2013

4. Oxidative stress injury in doxorubicin-induced cardiotoxicity;Songbo;Toxicol. Lett.,2019

5. Advances in delivery systems for doxorubicin;Zhao;J. Nanomed. Nanotechnol.,2018

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