MCC950 ameliorates the dementia symptom at the early age of line M83 mouse and reduces hippocampal α-synuclein accumulation-Reference-Cited by-同舟云学术

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MCC950 ameliorates the dementia symptom at the early age of line M83 mouse and reduces hippocampal α-synuclein accumulation

Published:2022-06 Issue: Volume:611 Page:23-30
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Ren Yu,Wang Qing,Yang Zexian,Feng Linyin,Zhang Yu

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference34 articles.

1. Lewy body dementias;Walker;Lancet (London, England),2015

2. Are dementia with Lewy bodies and Parkinson's disease dementia the same disease?;Jellinger;BMC Med.,2018

3. A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells;Zhang;Brain Res. Bull.,2022

4. Nasal rifampicin improves cognition in a mouse model of dementia with lewy bodies by reducing α-synuclein oligomers;Umeda;Int. J. Mol. Sci.,2021

5. The leukotriene receptor antagonist montelukast reduces alpha-synuclein load and restores memory in an animal model of dementia with lewy bodies;Marschallinger;Neurother.: J. Am. Soc. Exp. Neurother.,2020

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1. Inhibition of NLRP3 inflammasome ameliorates LPS-induced neuroinflammatory injury in mice via PINK1/Parkin pathway;Neuropharmacology;2024-10

2. Inhibition of NLRP3 inflammasome by MCC950 under hypoxia alleviates photoreceptor apoptosis via inducing autophagy in Müller glia;The FASEB Journal;2024-05-16

3. New Insights on NLRP3 Inflammasome: Mechanisms of Activation, Inhibition, and Epigenetic Regulation;Journal of Neuroimmune Pharmacology;2024-02-29

4. MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease;Brain, Behavior, and Immunity;2024-02

5. NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease;Neural Regeneration Research;2023-12-21

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