p.Q511L mutation of HNF1α in hepatocellular carcinoma suppresses the transcriptional activity and the anti-tumor effect of HNF1α-Reference-Cited by-同舟云学术

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p.Q511L mutation of HNF1α in hepatocellular carcinoma suppresses the transcriptional activity and the anti-tumor effect of HNF1α

Published:2018-01 Issue:1 Volume:495 Page:86-91
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Ding Chen-Hong,Deng Long-Fei,Chen Fei,Ding Kai,Chen Wan-Sheng,Xie Wei-Fen,Zhang Xin

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference28 articles.

1. Transcription factors in liver development, differentiation, and regeneration;Costa;Hepatology,2003

2. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha;Li;Genes Dev.,2000

3. Species-specific differences in the expression of the HNF1A, HNF1B and HNF4A genes;Harries;PLoS One,2009

4. HNF1alpha inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines;Pelletier;BMC Cancer,2011

5. Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors;Lazarevich;Hepatology,2004

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An intron mutation of HNF1A causes abnormal splicing and impairs its activity as a transcription factor;Molecular and Cellular Endocrinology;2022-04

2. HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks;Genes;2022-02-24

3. Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver;Cancers;2021-10-26

4. Integrated bioinformatic analysis of HNF1A in human cancers;Journal of International Medical Research;2021-03

5. The impact of hepatocyte nuclear factor-1α on liver malignancies and cell stemness with metabolic consequences;Stem Cell Research & Therapy;2019-11-04

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