3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design

Author:

Wang Jing-Fang,Wei Dong-Qing,Li Lin,Zheng Si-Yuan,Li Yi-Xue,Chou Kuo-Chen

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference44 articles.

1. Evaluation of the activity of CYP2C19 in Gujrati and Marwadi subjects living in Mumbasi (Bombay);Tanmay;BMC Clin. Pharm.,2006

2. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism;Gonzale;J. Nature,1988

3. Identification and functional characterization of eight CYP3A4 protein variants;Regina;Pharmacogenetics,2001

4. M. Ingelman-Sundberg, M. Oscarson, A. K. Daly, S. Garte, D. W. Nebert, Human cytochrome P450 (CYP) alleles a web page for the nomenclature of alleles [http://www.imm.ki.se/CYPalleles/] (accessed 22.11.2005).

5. Clinical significance of the cytochrome P450 2C19 genetic polymorphism;Desta;Clin. Pharmacokinet,2002

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