Artificial aptamer that inhibits interleukin-23/interleukin-23 receptor interaction discovered via SELEX

Author:

Takamori Yukio,Ando Takehiro,Sato Masashi,Vedi Santhana,Fuji Daisuke,Yokoyama Takumi,Tsukamoto Keita,Yamamoto Mizuki,Kawakami TakashiORCID

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Heiwa Nakajima Foundation

Precursory Research for Embryonic Science and Technology

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference23 articles.

1. IL-12 family cytokines: immunological playmakers;Vignali;Nat. Immunol.,2012

2. Current perspective on the role of the interleukin-23/interleukin-17 axis in inflammation and disease (chronic arthritis and psoriasis);Cauli;ImmunoTargets Ther.,2015

3. Interleukin-23: as a drug target for autoimmune inflammatory diseases;Tang;Immunology,2012

4. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12;Oppmann;Immunity,2000

5. Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis;Koutruba;Therapeut. Clin. Risk Manag.,2010

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