Exploratory drug safety: A discovery strategy to reduce attrition in development

Author:

Bass Alan S.,Cartwright Mark E.,Mahon Craig,Morrison Richard,Snyder Ronald,McNamara Paul,Bradley Prudence,Zhou Ying-Ying,Hunter John

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference61 articles.

1. Same old story?;Anon;Nature Reviews. Drug Discovery,2007

2. ICH guidance for industry — S7A safety pharmacology studies for human pharmaceuticals;Anon,2001

3. ICH guidance for industry – S7B nonclinical evaluation of the potential for delayed ventricular repolarization (QT interval prolongation) by human pharmaceuticals;Anon,2005

4. Assessment of chemical coverage of kinome space and its implications for kinase drug discovery;Bamborough;Journal of Medicinal Chemistr,2008

5. International life sciences institute (health and environmental sciences institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes;Bass;British Journal of Pharmacology,2008

Cited by 59 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Toxicology in drug research;Essentials of Pharmatoxicology in Drug Research, Volume 1;2023

2. Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs;Frontiers in Pharmacology;2022-07-01

3. Alzheimer’s Disease Drug Development: A Research and Development Ecosystem;Alzheimer's Disease Drug Development;2022-03-31

4. Central Nervous System (CNS) Safety Pharmacology Studies;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2022

5. In silico Modeling and Toxicity Profiling of a Set of Quinoline Derivatives as c-MET Inhibitors in the treatment of Human Tumors;Turkish Journal of Pharmaceutical Sciences;2021-12-30

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3