Cardiovascular safety assessments in the cynomolgus monkey: Unmasking potential background arrhythmias in general toxicity studies

Author:

Greiter-Wilke Andrea,Baird Ted,O'Donohue Kyle,Koerner Annette

Funder

F Hoffmann-La Roche Ltd.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference33 articles.

1. Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys;Authier;Journal of Pharmacological and Toxicological Methods,2010

2. Long-term outcomes in individuals with prolonged PR interval or 1° atrioventricular block;Cheng;Journal of the American Medical Association,2009

3. Comprehensive analysis of cardiac arrhythmias in telemetered cynomolgus monkeys over a 6month period;Chui;Journal of Pharmacological and Toxicological Methods,2012

4. ECG arrhythmias in non-implanted vs. telemetry-implanted dogs: Need for screening before and sufficient recovery time after implantation;Cools;Journal of Pharmacological and Toxicological Methods,2011

5. Evaluation and management of bradydysrhythmias in the emergency department;Deal;Emergency Medicine Practice,2013

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