Significance of integrated in silico transmural ventricular wedge preparation models of human non-failing and failing hearts for safety evaluation of drug candidates-Reference-Cited by-同舟云学术

Significance of integrated in silico transmural ventricular wedge preparation models of human non-failing and failing hearts for safety evaluation of drug candidates

Published:2017-01 Issue: Volume:83 Page:30-41
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Kubo Taeko,Ashihara Takashi,Tsubouchi Tadashi,Horie Minoru

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference45 articles.

1. Asymmetry in membrane responses to electric shocks: Insights from bidomain simulations;Ashihara;Biophysical Journal,2004

2. Vortex cordis as a mechanism of postshock activation: Arrhythmia induction study using a bidomain model;Ashihara;Journal of Cardiovascular Electrophysiology,2003

3. Reverse rate-dependent changes are determined by baseline action potential duration in mammalian and human ventricular preparations;Barandi;Basic Research in Cardiology,2010

4. Species differences in distribution and prediction of human V(ss) from preclinical data;Berry;Drug Metabolism and Disposition,2011

5. Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure;Beuckelmann;Circulation Research,1993

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Machine learning approach to evaluate TdP risk of drugs using cardiac electrophysiological model including inter-individual variability;Frontiers in Physiology;2023-10-04

2. Occurrence of early afterdepolarization under healthy or hypertrophic cardiomyopathy conditions in the human ventricular endocardial myocyte: In silico study using 109 torsadogenic or non-torsadogenic compounds;Toxicology and Applied Pharmacology;2022-03

3. Sex Differences in Drug-Induced Arrhythmogenesis;Frontiers in Physiology;2021-08-19

4. In silico models for evaluating proarrhythmic risk of drugs;APL Bioengineering;2020-06-01

5. Transmural and rate-dependent profiling of drug-induced arrhythmogenic risks through in silico simulations of multichannel pharmacology;Scientific Reports;2019-12