Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report

Author:

Mulder Petra,de Korte Tessa,Dragicevic Elena,Kraushaar Udo,Printemps RichardORCID,Vlaming Maria L.H.,Braam Stefan R.,Valentin Jean-Pierre

Funder

Horizon 2020

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference53 articles.

1. Assessment of extracellular field potential and Ca2 + transient signals for early QT/pro-arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes;Abi-Gerges;Journal of Pharmacological and Toxicological Methods,2017

2. A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes;Ando;Journal of Pharmacological and Toxicological Methods,2017

3. 1ICH S7B: The nonclinical evaluation of the potential for delayed ventricular repolarization. CQT interval prolongation by Human Pharmaceuticals;Anon,2005

4. ICH E14: The clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs;Anon,2005

5. Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes;Asakura;Journal of Pharmacological and Toxicological Methods,2015

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