A pharmacokinetic–pharmacodynamic model for cardiovascular safety assessment of R1551
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference27 articles.
1. Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies;Aarons;European Journal of Clinical Pharmacology,1996
2. Atrioventricular block revisited;Barold;Comprehensive Therapy,2002
3. NONMEM™ users guide 1998, NONMEM™ project group;Beal,1998
4. Developmental basis for electrophysiological heterogeneity in the ventricular and outflow tract myocardium as a substrate for life-threatening ventricular arrhythmias;Boukens;Circulation Research,2009
5. Drugs that prolong QT interval as an unwanted effect: Assessing their likelihood of inducing hazardous cardiac dysrhythmias;Cavero;Expert Opinion on Pharmacotherapy,2000
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