Application of simple mathematical expressions to relate the half-lives of xenobiotics in rats to values in humans

Author:

Ward Keith W.,Erhardt Paul,Bachmann Kenneth

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference23 articles.

1. The use of primates under the animals (scientific procedures) act (1986): Analysis of current trends with particular reference to regulatory toxicology;Animal Procedures Committee,2002

2. Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species;Bachmann;Journal of Applied Toxicology,1989

3. Scaling basic toxicokinetic parameters from rat to man;Bachmann;Environmental Health Perspectives,1996

4. Determining the best animal model for human cytochrome P450 activities: A comparison of mouse, rat, rabbit, dog, minipig, monkey and man;Bogaards;Xenobiotica,2000

5. Critique of prospective allometric scaling: Does the emperor have clothes?;Bonate;Journal of Clinical Pharmacology,2000

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