A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability-Reference-Cited by-同舟云学术

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A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability

Published:2022-03 Issue: Volume:114 Page:107154
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Blanchette Alexander D.,Burnett Sarah D.,Rusyn Ivan,Chiu Weihsueh A.

Funder

U.S. Environmental Protection Agency

National Institutes of Health

National Institute of Environmental Health Sciences

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference35 articles.

1. Population-based in vitro hazard and concentration–response assessment of chemicals: The 1000 genomes high-throughput screening study;Abdo;Environmental Health Perspectives,2015

2. Risk factors for prolonged QTc among US adults: Third National Health and nutrition examination survey;Benoit;European Journal of Cardiovascular Prevention and Rehabilitation,2005

3. A Bayesian method for population-wide cardiotoxicity Hazard and risk characterization using an in vitro human model;Blanchette;Toxicological Sciences,2020

4. Thorough QT/QTc in a dish: An in vitro human model that accurately predicts clinical concentration-QTc relationships;Blanchette;Clinical Pharmacology & Therapeutics,2019

5. Clinical trial in a dish: Personalized stem cell-derived cardiomyocyte assay compared with clinical trial results for two QT-prolonging drugs;Blinova;Clinical and Translational Science,2019

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1. Characterizing PFAS hazards and risks: a human population-based in vitro cardiotoxicity assessment strategy;Human Genomics;2024-09-02

2. Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin;Toxicological Sciences;2024-03-28

3. Evaluating scientific confidence in the concordance of in vitro and in vivo protective points of departure;Regulatory Toxicology and Pharmacology;2024-03

4. Why adverse outcome pathways need to be FAIR;ALTEX;2024

5. Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes;Journal of Molecular Liquids;2023-10

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