Safety pharmacology assessment of drug-induced QT-prolongation in dogs with reduced repolarization reserve

Author:

Vormberge Thomas,Hoffmann Michael,Himmel Herbert

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference30 articles.

1. Droperidol exerts dual effects on repolarization and induces early after depolarizations and triggered activity in rabbit Purkinje fibers;Adamantidis;Journal of Pharmacology and Experimental Therapeutics,1993

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3. Assessing predictors of drug-induced torsade de pointes;Belardinelli;Trends in Pharmacological Sciences,2003

4. Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: Role of repolarization reserve;Biliczki;British Journal of Pharmacology,2002

5. Do existing measures of Poincare plot geometry reflect nonlinear features of heart rate variability?;Brennan;IEEE Transactions on Biomedical Engineering,2001

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