Carbon dioxide: A reagent for the protection of nucleophilic centres and the simultaneous activation of electrophilic attack
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference18 articles.
1. Dipole-stabilized carbanions: novel and useful intermediates
2. Metalation and electrophilic substitution of amine derivatives adjacent to nitrogen: .alpha.-metallo amine synthetic equivalents
3. 2-Bis (dimethylamino)phosphinoyl-1-lithio-1, 2, 3, 4-tetrahydroisoquinoline. A highly nucleophilic d1-reagent for the preparation of 1-substituted tetrahydroisoquinolines
4. LithiatedN-pivaloyl-tetrahydroisoquinoline?a Supernuclephile
5. Alkylation of the isoquinoline skeleton in the 1-position
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1. In Situ Protecting Groups for Chemoselective Transformations;Methods in Pharmacology and Toxicology;2021-12-14
2. Synthesis of substituted tetrahydroisoquinolines by lithiation then electrophilic quench;Organic & Biomolecular Chemistry;2016
3. Is Carbon Dioxide Able to Activate Halogen/Lithium Exchange?;European Journal of Organic Chemistry;2014-06-16
4. Synthesis of 1-Substituted Tetrahydroisoquinolines by Lithiation and Electrophilic Quenching Guided by In Situ IR and NMR Spectroscopy and Application to the Synthesis of Salsolidine, Carnegine and Laudanosine;Chemistry - A European Journal;2013-05-15
5. Facile synthesis and in vitro properties of 1-alkyl- and 1-alkyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline derivatives on PC12 cells;European Journal of Medicinal Chemistry;2009-10
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