New synthesis of 2',3'-dideoxy-3'-C-cyano-2'-substituted thymidines by michael addition reactions
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference35 articles.
1. Investigations on the anti-HIV activity of 2′, 3′-dideoxyadenosine analogues with modifications in either the pentose or purine moiety
2. The Quest for Therapy
3. Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogs
4. B. Öberg & R. Datema, Astra Läkemedel AB, Sweden, (Personal Comm.).
5. Methyl 5-0--butyldiphenylsilyl-2-deoxy-α β -d--pentofuranoside as a divergent intermediate for the synthesis of 3'-substituted-2',3'-dideoxynucleosides: synthesis of 3'-azido-3'-deoxythymidine, 3'-deoxy-3'-fluorothymidine and 3'-cyano-3'-deoxythymidine.
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1. Michael Addition;Comprehensive Organic Name Reactions and Reagents;2010-09-15
2. Synthesis, Structure, and Conformation of 2′,3′-Fused Oxathiane and Thiomorpholine Uridines;Helvetica Chimica Acta;2007-10
3. Synthesis of 2′,3′-didehydro-2′,3′-dideoxynucleosides having variations at either or both of the 2′- and 3′-positions;Tetrahedron;2006-09
4. Asymmetric synthesis of thymine nucleoside analogues based on the isochroman core;Tetrahedron Letters;2005-07
5. Reactivity and diastereoselectivity of Michael additions of amines to achiral α,β-unsaturated thioamides;Tetrahedron;2001-10
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