Timing of pre-dose baseline electrocardiograms in clinical trials: Increased sampling over a prolonged baseline period worsens variance of QTc-Reference-Cited by-同舟云学术

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Timing of pre-dose baseline electrocardiograms in clinical trials: Increased sampling over a prolonged baseline period worsens variance of QTc

Published:2014-09 Issue:5 Volume:47 Page:716-720
ISSN:0022-0736
Container-title:Journal of Electrocardiology
language:en
Short-container-title:Journal of Electrocardiology

Author:

Mason Jay W.

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference21 articles.

1. Effect of number of replicate electrocardiograms recorded at each time point in a thorough QT study on sample size and study cost;Natekar;J Clin Pharmacol,2011

2. Circadian profile of QT interval and QT interval variability in 172 healthy volunteers;Bonnemeier;Pacing Clin Electrophysiol,2003

3. Circadian rhythm of the corrected QT interval: impact of different heart rate correction models;Smetana;Pacing Clin Electrophysiol,2003

4. A multivariate Kolmogorov–Smirnov test of goodness of fit;Justel;Stat Probab Lett,1997

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