Is reduced systemic heparinization justified with heparin-bonded bypass circuits in cardiac surgery?––Experience with and without aprotinin
Author:
Publisher
Elsevier BV
Subject
Hematology
Reference22 articles.
1. Heparin bonding of bypass circuits reduces cytokine release during cardiopulmonary bypass;Steinberg;Ann. Thorac. Surg.,1995
2. Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits;Aldea;J. Thorac. Cardiovasc. Surg.,2002
3. High dose aprotinin reduces prothormbin and fibrinogen conversion in patients undergoing extracorporeal circulation for myocardial revascularization;Spannagel;Thromb. Haemost.,1994
4. Kinetic analysis of a unique direct prothrombinase, fgl2, and identification of a serine residue critical for the prothrombinase activity;Chan;J. Immunol.,2002
5. Pharmacokinetics of aprotinin in preoperative cardiac surgical patients;Levy;Anesthesiology,1994
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1. Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults;Cochrane Database of Systematic Reviews;2023-10-24
2. Heparinized cardiopulmonary bypass circuits and low systemic anticoagulation: An analysis of nearly 6000 patients undergoing coronary artery bypass grafting;The Journal of Thoracic and Cardiovascular Surgery;2011-05
3. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion;Cochrane Database of Systematic Reviews;2011-03-16
4. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion;Cochrane Database of Systematic Reviews;2011-01-19
5. Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study;Interactive CardioVascular and Thoracic Surgery;2010-01-12
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