Mechanisms of resistance to topoisomerases poisons

Author:

Prost S.

Publisher

Elsevier BV

Subject

Pharmacology

Reference88 articles.

1. Identification of an N-terminal domaine of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function;Alsern;J. Biol. Chem.,1992

2. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I;Andoh,1987

3. Isolation and characterization of a human cDNA clone encoding a novel DNA topoisomerase II homologue from HeLa cells;Austin;FEBS Letters,1990

4. Cell death in health and disease; the biology and regulation of apoptosis;Bellamy;Semin. Cancer Biol.,1995

5. Expression of human DNA Topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumour drug camptothecin;Bjornsti;Cancer Res.,1989

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