Development, pharmacology, role of DT-diaphorase and prospects of the indoloquinone EO9

Author:

Smitskamp-Wilms E.,Hendriks H.R.,Peters G.J.

Publisher

Elsevier BV

Subject

Pharmacology

Reference88 articles.

1. Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR4233 and the Mitomycin C analogue EO9;Adams;Int. J. Radiat. Oncol. Biol. Phys.,1992

2. Involvement of DT-diaphorase in the DNA cross-linking and sequence selectivity of the novel indoloquinone antitumour agent EO9;Bailey,1994

3. Involvement of NADPH: Cytochrome P450 reductase in activation of EO9;Bailey;Br. J. Cancer,1994

4. Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones;Bailey;Int. J. Radiat. Oncol. Biol. Physics,1992

5. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases;Beall;Cancer Res.,1994

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