A Peptidylic Inhibitor for Neutralizing (GGGGCC)-Associated Neurodegeneration in C9ALS-FTD-Reference-Cited by-同舟云学术

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A Peptidylic Inhibitor for Neutralizing (GGGGCC)-Associated Neurodegeneration in C9ALS-FTD

Published:2019-06 Issue: Volume:16 Page:172-185
ISSN:2162-2531
Container-title:Molecular Therapy - Nucleic Acids
language:en
Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Zhang Qian,An Ying,Chen Zhefan Stephen,Koon Alex Chun,Lau Kwok-Fai,Ngo Jacky Chi Ki,Chan Ho Yin Edwin

Funder

Hong Kong Research Grants Council

CUHK Lui Che Woo Institute of Innovative Medicine BRAIN Initiative

CUHK Group Research Scheme

CUHK Vice-Chancellor’s One-Off Discretionary Fund

CUHK One-off Funding for Joint Lab/Research Collaboration

CUHK Gerald Choa Neuroscience Centre

CUHK Faculty of Science Strategic Development Fund

Hong Kong Spinocerebellar Ataxia Association

Postdoctoral Fellowship in Clinical Neurosciences of The Chinese University of Hong Kong

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference73 articles.

1. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS;DeJesus-Hernandez;Neuron,2011

2. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD;Renton;Neuron,2011

3. Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 Locus;Hu;Chem. Biol.,2015

4. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia;Zu;Proc. Natl. Acad. Sci. USA,2013

5. Mechanisms of toxicity in C9FTLD/ALS;Gendron;Acta Neuropathol.,2014

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD;Nature Communications;2023-12-18

2. Neurobiochemical characteristics of arginine-rich peptides explain their potential therapeutic efficacy in neurodegenerative diseases;Neuropeptides;2023-10

3. Targeting the nucleolus as a therapeutic strategy in human disease;Trends in Biochemical Sciences;2023-03

4. A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins;Science Translational Medicine;2023-03

5. Therapeutic Potential of CPPs;CPP, Cell-Penetrating Peptides;2023

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