A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition-Reference-Cited by-同舟云学术

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A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition

Published:2023-06 Issue: Volume:32 Page:553-565
ISSN:2162-2531
Container-title:Molecular Therapy - Nucleic Acids
language:en
Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Chinnapaiyan Srinivasan,Santiago Maria-Jose,Panda Kingshuk,Rahman Md. Sohanur,Alluin Jessica,Rossi John,Unwalla Hoshang J.

Funder

National Heart Lung and Blood Institute

Congressionally Directed Medical Research Programs

National Institutes of Health

US Department of Defense

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference44 articles.

1. CRISPR/Cas9 systems targeting beta-globin and CCR5 genes have substantial off-target activity;Cradick;Nucleic Acids Res.,2013

2. CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets;Tsai;Nat. Methods,2017

3. Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing;Wang;Sci. Rep.,2020

4. Off-target effects in CRISPR/Cas9-mediated genome engineering;Zhang;Mol. Ther. Nucleic Acids,2015

5. Drug inducible CRISPR/cas systems;Zhang;Comput. Struct. Biotechnol. J.,2019

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1. Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology;Pharmaceuticals;2024-07-04

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