Large-Fragment Deletions Induced by Cas9 Cleavage while Not in the BEs System-Reference-Cited by-同舟云学术

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Large-Fragment Deletions Induced by Cas9 Cleavage while Not in the BEs System

Published:2020-09 Issue: Volume:21 Page:523-526
ISSN:2162-2531
Container-title:Molecular Therapy - Nucleic Acids
language:en
Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Song Yuning,Liu Zhiquan,Zhang Yuxin,Chen Mao,Sui Tingting,Lai Liangxue,Li Zhanjun

Funder

National Key Research and Development Program of China Stem Cell and Translational Research

Strategic Priority Research Program of the Chinese Academy of Sciences

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference18 articles.

1. Multiplex genome engineering using CRISPR/Cas systems;Cong;Science,2013

2. Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects;Shen;Nat. Methods,2014

3. Large deletions induced by Cas9 cleavage;Adikusuma;Nature,2018

4. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells;Fu;Nat. Biotechnol.,2013

5. Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements;Kosicki;Nat. Biotechnol.,2018

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