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Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy

  • Published:2021-03 Issue: Volume:23 Page:393-405
  • ISSN:2162-2531
  • Container-title:Molecular Therapy - Nucleic Acids
  • language:en
  • Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Hu Ningyan,Kim Eunjoo,Antoury Layal,Li Jia,González-Pérez Paloma,Rutkove Seward B.,Wheeler Thurman M.

Funder

National Institutes of Health

Muscular Dystrophy Association

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference65 articles.

1. Myotonic Dystrophy;Harper,1989

2. Consensus-based care recommendations for adults with myotonic dystrophy type 1;Ashizawa;Neurol. Clin. Pract.,2018

3. Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member;Brook;Cell,1992

4. Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy;Harley;Am. J. Hum. Genet.,1993

5. Allele length of the DMPK CTG repeat is a predictor of progressive myotonic dystrophy type 1 phenotypes;Overend;Hum. Mol. Genet.,2019

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