Activity of pembrolizumab and lenvatinib in mismatch repair deficient (dMMR) endometrial cancer patients who have failed pembrolizumab monotherapy: A case series

Author:

Rose Peter G.ORCID,Feldman Myra,Podzielinski Iwona,Petty Aaron P.,Vargas Roberto

Publisher

Elsevier BV

Subject

Obstetrics and Gynecology,Oncology

Reference12 articles.

1. Center for Drug Evaluation and Research, 2022. FDA grants regular approval to pembrolizumab and lenvatinib for advanced endometrial carcinoma [WWW Document]. FDA. URL https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-regular-approval-pembrolizumab-and-lenvatinib-advanced-endometrial-carcinoma (accessed 9.26.23).

2. Phase 2 trial of nonpegylated doxorubicin (Myocet) as second-line treatment in advanced or recurrent endometrial cancer;Di Legge;Int J Gynecol Cancer.,2011

3. Pembrolizumab plus chemotherapy in advanced endometrial cancer;Eskander;N. Engl. J. Med.,2023

4. Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1-6 hepatocellular carcinoma model;Kimura;Cancer Sci.,2018

5. Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: An interim analysis of a multicentre, open-label, single-arm, phase 2 trial;Makker;Lancet Oncol,2019

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