Enzymatic synthesis of β-lactam antibiotics using penicillin-G acylase in frozen media
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/S0014-5793(99)00939-4/fullpdf
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1. Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular dd-carboxypeptidase–transpeptidase of Streptomyces R61
2. Acyl group transfer by proteases forming acyl-enzyme intermediate: Kinetic model analysis
3. Ionic strength and pH effects in the kinetically controlled synthesis of benzylpenicillin by nucleophilic deacylation of pree and immobilized phenyl-acetyl-penicillin amidase with 6-aminopenicillanic acid
4. Kinetically Controlled Semisynthesis of β-Lactam Antibiotics and Peptidesa
5. The second nucleophile molecule binds to the acyl-enzyme-nucleophile complex in alpha-chymotrypsin catalysis. Kinetic evidence for the interaction
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