Disruption of γ-glutamylcysteine synthetase results in absolute glutathione auxotrophy and apoptosis inCandida albicans
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/S0014-5793(03)01363-2/fullpdf
Reference38 articles.
1. GLUTATHIONE
2. Glutathione is an essential metabolite required for resistance to oxidative stress in the yeastSaccharomyces cerevisiae
3. GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation.
4. apd1 +, a Gene Required for Red Pigment Formation in ade6 Mutants of Schizosaccharomyces pombe, Encodes an Enzyme Required for Glutathione Biosynthesis: A Role for Glutathione and a Glutathione-Conjugate Pump
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