Clinical studies in the development of new anticancer agents exhibiting growth inhibition in models: facing the challenge of a proper study design

Author:

Eskens Ferry A.L.M,Verweij Jaap

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference13 articles.

1. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice;Kohl;Nat. Med.,1995

2. Treatment with farnesyl protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) α and TGFα/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis;Nørgaard;Clin. Cancer Res.,1999

3. Tumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase in human tumor xenograft models in wap-ras transgenic mice;Liu;Cancer Res.,1998

4. A phase I and pharmacologic study of the farnesyl protein transferase (FPT) inhibitor SCH 66336 in patients with locally advanced or metastatic cancer;Adjei;Proc. Am. Soc. Clin. Oncol.,1999

5. Matrixmetalloproteinase inhibitors: present achievements and future prospects;Denis;Invest. New Drugs,1997

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