Immunotherapy: opportunities, risks and future perspectives

Author:

Hildebrandt Martin,Peggs Karl,Uharek Lutz,Bollard Catherine M.,Heslop Helen E.

Publisher

Elsevier BV

Subject

Cancer Research,Transplantation,Cell Biology,Genetics(clinical),Oncology,Immunology,Immunology and Allergy

Reference68 articles.

1. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia;Kalos;Sci Transl Med,2011

2. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia;Brentjens;Sci Transl Med,2013

3. Bollard CM, Gottschalk S, Torrano V, Diouf O, Ku S, Hazrat Y, et al. Sustained complete responses in lymphoma patients receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane protein [published online ahead of print December 16, 2013]. J Clin Oncol.

4. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells;Kochenderfer;Blood,2012

5. Durable complete responses in heavily pretreated patients with metastatic melanoma using T cell transfer immunotherapy;Rosenberg;Clin Cancer Res,2011

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