Failure to launch commercially-approved mesenchymal stromal cell therapies: what's the path forward? Proceedings of the International Society for Cell & Gene Therapy (ISCT) Annual Meeting Roundtable held in May 2023, Palais des Congrès de Paris, Organized by the ISCT MSC Scientific Committee

Author:

Robb Kevin P.,Galipeau JacquesORCID,Shi Yufang,Schuster Michael,Martin IvanORCID,Viswanathan Sowmya

Publisher

Elsevier BV

Subject

Cancer Research,Transplantation,Cell Biology,Genetics (clinical),Oncology,Immunology,Immunology and Allergy

Reference44 articles.

1. Mesenchymal stromal cells: clinical challenges and therapeutic opportunities;Galipeau;Cell Stem Cell,2018

2. Mesenchymal stem cell perspective: cell biology to clinical progress;Pittenger;NPJ Regen Med,2019

3. The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?;Galipeau;Cytotherapy,2013

4. Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses;Costa;Cell Mol Life Sci,2021

5. Mesoblast Limited. Mesoblast resubmits biologic license application (BLA) to FDA for remestemcel-l in children with steroid-refractory acute graft versus host disease (SR-aGVHD). https://investorsmedia.mesoblast.com/static-files/60aa26a8-85ce-4735-8fa6-2b0769eb6120; 2023 [accessed 9.8.23].

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