Incongruity between T cell receptor recognition of breast cancer hotspot mutations ESR1 Y537S and D538G following exogenous peptide loading versus endogenous antigen processing

Author:

Shafer Paul,Leung Wingchi K.ORCID,Woods MaeORCID,Choi Jong Min,Rodriguez-Plata Carlos M.ORCID,Maknojia ArushanaORCID,Mosquera AndresORCID,Somes Lauren K.ORCID,Joubert JarrettORCID,Manliguez Anthony,Ranjan RashiORCID,Burt Bryan,Lee Hyun-SungORCID,Zhang BingORCID,Fuqua SuzanneORCID,Rooney ClionaORCID,Leen Ann M.ORCID,Hoyos ValentinaORCID

Publisher

Elsevier BV

Reference50 articles.

1. Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma;Ramachandran;J. Immunother. Cancer,2019

2. SPEARHEAD-1: A phase 2 trial of afamitresgene autoleucel (Formerly ADP-A2M4) in patients with advanced synovial sarcoma or myxoid/round cell liposarcoma [Conference presentation];D'Angelo,2021

3. Phase I dose escalation and expansion trial to assess the safety and efficacy of ADP-A2M4 SPEAR T cells in advanced solid tumors [Conference presentation];Hong,2020

4. A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1–Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response;Robbins;Clin. Cancer Res.,2015

5. TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers;Nagarsheth;Nat. Med.,2021

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